Polynucleotides – Plinest® Eyes & Plinest® Face
What is Polynucleotides – Plinest® Eyes & Plinest® Face?
Polynucleotides have been used in medicine since the 1970s to treat burns and support wound healing. More recently, they have become an exciting development in aesthetic medicine for skin regeneration and rejuvenation.
The polynucleotides used in these treatments are derived from highly purified, sterilised fish DNA. When injected into the skin, they help stimulate cell repair and regeneration, improving hydration, reducing inflammation, and encouraging fibroblast activity – the cells responsible for producing collagen and elastin. The result is healthier, firmer, brighter, and more radiant-looking skin.
As a registered nurse and independent prescriber, Nichola is fully qualified to assess your suitability, prescribe, and safely administer these treatments using advanced techniques tailored to your needs.
M. 07760225486
E. info@aestheticsbynichola.co.uk
Plinest® Eyes – Under-Eye Regeneration
Plinest® Eyes is a unique polynucleotide-based treatment designed specifically for the delicate under-eye area. It is ideal for improving:
Dark circles
Puffiness and swelling
Fine lines and wrinkles
Crepey, fragile under-eye skin
By regenerating tissue quality from within, Plinest® Eyes helps restore a brighter, smoother, and more refreshed appearance.
Plinest® Face – Skin Regeneration
Plinest® Face is a biostimulation treatment that uses purified polynucleotides (PN-HPT®) to deeply regenerate the skin from within. It works at a cellular level to:
Improve elasticity and firmness
Enhance hydration
Refine texture and tone
Restore radiance and overall skin health
Plinest® Face is highly biocompatible, safe, and clinically proven. It is ideal for anyone wanting to restore skin health, firmness, and glow without adding volume or changing facial structure.
Polynucleotides – Plinest® Eyes & Plinest® Face Procedure:
Consultation
Your treatment begins with a thorough consultation with Nichola, where you can discuss your concerns and desired outcomes. Nichola will carefully assess the treatment area—whether under the eyes or the face—and advise honestly on suitability. As a registered nurse and independent prescriber, she will create an individualised plan tailored specifically to your needs.
Appointment
Before treatment begins, a topical numbing cream is applied to ensure comfort throughout the procedure. This is especially helpful for polynucleotide treatments, as they can cause a mild stinging sensation when injected.
Nichola will then deliver the product using precise microinjections with ultra-fine Nanosoft needles, or a cannula where appropriate. These techniques allow the product to be placed accurately either:
Under and around the eyes (Plinest® Eyes), or
Across areas of the face requiring regeneration (Plinest® Face).
Because the needles are extremely fine, the risk of bruising or bleeding is low, and most clients find the procedure very well tolerated.
Treatment plan
We will then discuss a personalised treatment plan. Most clients require an initial course of three treatments, spaced 2–3 weeks apart, to achieve optimal regeneration and long-lasting results.
Maintenance sessions are recommended every 4–6 months (or around every 6 months for the under-eye area), with results typically lasting 6–9 months depending on individual skin quality and lifestyle.
Polynucleotides – Plinest® Eyes & Plinest® Face Aftercare Advice
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Keep the treated area clean and free from makeup to minimise the risk of irritation or infection while the skin begins to heal.
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Saunas, steam rooms, hot baths, and vigorous exercise can increase swelling and should be avoided for the first 1–2 days.
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Drinking plenty of water supports the skin’s repair process and helps enhance the regenerative effects of polynucleotides.
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Alcohol can thin the blood and increase the risk of bruising, so it’s best avoided around your appointment.
BeautifEYE NCTF® 135HA – Frequently Asked Questions FAQs
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Polynucleotides are purified DNA fragments derived from sterilised fish DNA. They help repair and regenerate the skin by improving hydration, reducing inflammation, and stimulating collagen and elastin production.
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These treatments deliver polynucleotides directly into the skin, encouraging tissue repair and cellular regeneration. This improves texture, firmness, hydration, and overall skin quality, while reducing fine lines, dark circles, and signs of fatigue.
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Polynucleotides can improve:
Dark circles and under-eye puffiness
Crepey, thin under-eye skin
Fine lines and wrinkles
Dull or dehydrated skin
Uneven texture and tone
Loss of firmness and elasticity
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A numbing cream is applied before treatment to ensure comfort. You may experience mild stinging, but most clients find the procedure very tolerable.
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Downtime is minimal. Small bumps may appear at the injection sites and normally settle within 12–24 hours.
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Most clients require an initial course of three treatments, spaced 2–3 weeks apart. Maintenance treatments every 4–6 months help keep the results long-lasting.
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Some improvements can be seen after the first session, but the most noticeable results appear over several weeks as collagen and elastin production increases.
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Results typically last 6–9 months, depending on your skin quality, lifestyle, and maintenance treatments.
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Yes. Plinest® products are highly purified, biocompatible, and widely used in both medical and aesthetic settings. As a registered nurse and independent prescriber, Nichola ensures treatments are carried out safely and appropriately.
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This treatment is not recommended for individuals who are:
Pregnant or breastfeeding
Experiencing active skin infections or inflammation
Living with severe allergies or specific medical contraindications
Suitability is always assessed during consultation.
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Yes. They pair well with treatments such as Profhilo®, anti-wrinkle injections, and skin boosters. Nichola will advise you on safe and effective combination plans.